The vulnerability of cancer cells to nutrient deprivation and their dependency on specific metabolites are emerging hallmarks of cancer. Fasting or fasting-mimicking diets (FMDs) lead to wide alterations in growth factors and in metabolite…
To synchronize a network of pacemakers in the Drosophila brain, a neuropeptide receptor specifically associates with adenylate cyclase 3 to create a “circadian signalosome.”
Research in my laboratory is focused on immune cells called T regulatory cells (Tregs) that are central to immune tolerance and that are a very promising new therapeutic tool. To exploit the natural capacity of Tregs to induce immune…
Published in the journal: . PLoS Genet 11(9): e32767. doi:10.1371/journal.pgen.1005484 Category: Research Article doi: https://doi.org/10.1371/journal.pgen.1005484
The disciplines of cellular and molecular biology are being rapidly and dramatically transformed by the application of fluorescent proteins developed from marine organisms as fusion tags to track protein behavior in living cells.