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The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled receptor family, cannabinoid receptors 1 (CB1R) and 2.
Geneva (/ dʒ ɪ ˈ n iː v ə/ jin- EE-və, [5 ] Arpitan: [dzəˈnɛva] ; French: Genève [ʒ(ə)nɛv] ) [note 1 ] is the second-most populous city in Switzerland and the most populous in French-speaking Romandy.
Transient Receptor Potential Vanilloid 1 (TRPV1) is a non-selective, Ca2+ permeable cation channel activated by noxious heat, and chemical ligands, such as capsaicin and resiniferatoxin (RTX).