Optic neuritis (ON) may involve the retrobulbar (retrobulbar neuritis) or the intrabulbar (papillitis) portion of the optic nerve, or both. Idiopathic ON, the most common form of ON, is an inflammatory optic neuropathy in the absence of…
While amyloid-beta (Aβ) peptide deposition into insoluble plaques is a pathological hallmark of Alzheimer’s disease, soluble oligomeric Aβ has been hypothesized to more directly underlie impaired learning and memory in dementia of the…
Finally, we discuss practical challenges to the wider adoption of molecular profiling in the clinic and the need for robust translational infrastructure.
Execution of fundamental cellular functions demands regulated protein folding homeostasis. Endoplasmic reticulum (ER) is an active organelle existing to implement this function by folding and modifying secretory and membrane proteins.
The goal of this review has been to elucidate the sex differences in cancer incidence and mortality in cutaneous melanoma. We have evaluated biological and behavioral research to determine where the critical questions exist.
It combines a radio, computer, and a tactical voice privacy unit into a state-of-the-art communications system that meets the demanding requirements of Customs' tactical interdiction aircraft and boats in their fight against smuggling…
During January 2024, we commissioned research company Opinion Matters to survey the opinions of over 3,500 business leaders and insurance buyers of businesses based in the UK, US, Canada, Singapore, France, Germany and Spain with…
Spy0269, spy0469, spy1228, spy1643, spy1801 and spy2010 showed the highest IgG responses (Fig. 1, and Supplementary figure 1 that shows the plasma titration curves used to calculate the EC50 values).