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Nitric Oxide in Asthma Physiopathology - PMC

pmc.ncbi.nlm.nih.gov/articles/pmc3658695

Asthma is a chronic inflammatory airway disease characterized by allergen-induced airway hyperresponsiveness, airway inflammation, and remodeling. Nitric oxide (NO) derived from constitutive and inducible enzymes affects many aspects of…

Platelets: a critical link between inflammation and…

pmc.ncbi.nlm.nih.gov/articles/pmc3381810

Inflammation is an underlying feature of a variety of human diseases. An important manifestation of this pathophysiological response is microvascular dysfunction, which includes the activation of vascular endothelial cells, and circulating…

A high-salt diet enhances leukocyte adhesion in association…

pmc.ncbi.nlm.nih.gov/articles/pmc5675900

Salt-sensitive hypertension is associated with severe organ damage. Generating oxygen radicals is an integral component of salt-induced kidney damage, and activated leukocytes are important in oxygen radical biosynthesis.

Rosmarinic Acid Attenuates Airway Inflammation and…

mdpi.com/1420-3049/21/6/769

Rosmarinic acid (RA) has numerous pharmacologic effects, including anti-oxidant, anti-inflammatory, and analgesic effects. This study aimed to evaluate the preventive activity of RA in a murine model of asthma and to investigate its…

Nitrite Anion (NO2−) Provides Potent Cytoprotective and Anti…

pmc.ncbi.nlm.nih.gov/articles/pmc2587279

Accumulating evidence suggests that the ubiquitous anion nitrite (NO2−) is a physiological signaling molecule, with roles in intravascular endocrine nitric oxide (NO) transport, hypoxic vasodilation, signaling, and cytoprotection.