The variant impact was first evaluated using computational modeling. Functional analyses included activity assays, cellular Pnlip partition assessments, and endoplasmic reticulum (ER) stress evaluation in transfected cells.
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CMB-S4 is intended to be the definitive ground-based CMB project. It will deliver a highly constraining data set with which any model for the origin of the primordial fluctuations—be it inflation or an alternative theory—and their evolution…