The Impact of Exercise on Telomere Length, DNA Methylation and…
Aging as a major risk factor influences the probability of developing cancer, cardiovascular disease and diabetes, amongst others. The underlying mechanisms of disease are still not fully understood, but research suggests that delaying the…
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Myc - Wikipedia
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the…
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List of buildings at Florida State University - Wikipedia
As is typical in the United States, most of the university's buildings were designed in the Collegiate Gothic architectural style; the last being Cawthon Hall dormitory in 1949.
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High-throughput telomere length quantification by FISH and its…
A major limitation of studies of the relevance of telomere length to cancer and age-related diseases in human populations and to the development of telomere-based therapies has been the lack of suitable high-throughput (HT) assays to…
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Pui-Yan Kwok | UCSF Profiles
Pui-Yan Kwok's profile, publications, research topics, and co-authors
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Loss of epigenetic information as a cause of mammalian aging…
All living things experience an increase in entropy, manifested as a loss of genetic and epigenetic information. In yeast, epigenetic information is lost over time due to the relocalization of chromatin-modifying proteins to DNA breaks…
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Carotenoids in Drug Discovery and Medicine: Pathways and…
Carotenoids are isoprenoid-derived natural products produced in plants, algae, fungi, and photosynthetic bacteria. Most animals cannot synthesize carotenoids because the biosynthetic machinery to create carotenoids de novo is absent in…
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EurekaMag Full Text Articles Chapter 29251
Full Text Articles available from EurekaMag Chapter 29251
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Telomerase reverses epidermal hair follicle stem cell defects…
Organ homeostasis and organismal survival are related to the ability of stem cells to sustain tissue regeneration. As a consequence of accelerated telomerase shortening, telomerase-deficient mice show defective tissue regeneration and…
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SIRT1 contributes to telomere maintenance and augments global…
These findings link SIRT1 to telomere biology and global DNA repair and provide new mechanistic explanations for the known functions of SIRT1 in protection from DNA damage and some age-associated pathologies.
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