The human superorganism is a conglomerate of mammalian and microbial cells, with the latter estimated to outnumber the former by ten to one and the microbial genetic repertoire (microbiome) to be approximately 100-times greater than that of…
Gut microbiota is emerging as a key regulator of many disease conditions and its dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal disorders.
Studies examining the mechanisms by which the liver injures and regenerates usually focus on factors and pathways within the liver, neglecting the signaling derived from the gut-liver axis.
Anemia is the most prevalent extraintestinal complication of inflammatory bowel disease (IBD). [9 ] [10 ] Associated complaints or diseases include arthritis, pyoderma gangrenosum, primary sclerosing cholangitis, and non-thyroidal illness…
This review elaborates the development of germfree and gnotobiotic animal models and their application in the scientific field to unravel mechanisms underlying host–microbe interactions and distinct diseases.
Each individual is provided with a unique gut microbiota profile that plays many specific functions in host nutrient metabolism, maintenance of structural integrity of the gut mucosal barrier, immunomodulation, and protection against…
Circulating bile acids as a link between the gut microbiota and cardiovascular health: impact of prebiotics, probiotics and polyphenol-rich foods - Volume 35 Issue 2
Gut microbiota, cognitive frailty and dementia in older individuals: a systematic review Andrea Ticinesi,1–3 Claudio Tana,2 Antonio Nouvenne,2,3 Beatrice Prati,2 Fulvio Lauretani,2 Tiziana Meschi1–3 1Department of Medicine and Surgery…
Table 1. Symptom-based Criteria for the Diagnosis of Irritable Bowel Syndrome Abdominal pain relieved At least 12 weeks of consecutive, in thepreceding 12 monthsof abdominal discomfortor pain that has twoof the three features: Altered stool…