Mitochondrial dysfunction is implicated in a spectrum of human diseases. In this review, Pagliarini and Rutter recap the discoveries that defined the core functions of mitochondria, the mitochondrial proteome, and the functions of…
Liebl K, Aschenbrenner I, Schiller L, Kerle A, Protzer U, Feige MJ. Modeling of the human interleukin 12:receptor complex allows to engineer attenuated cytokine variants.