The neuromuscular junction (NMJ) is a synapse between motor neurons and skeletal muscle fibers, and is critical for control of muscle contraction. Its formation requires neuronal agrin that acts by binding to LRP4 to stimulate MuSK.
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There is substantial interest in the therapeutic potential of cannabidiol (CBD), a non-psychoactive cannabinoid found in plants of the genus Cannabis. The goal of the current systematic review was to characterize the existing literature on…
Elaine H. Zackai, MD, is the Senior Clinical Geneticist at Children's Hospital of Philadelphia. She holds the Endowed Chair in Clinical Genetics in the Department of Pediatrics and is a Professor, Division of Human Genetics, Department of…