Johan VAN NES, Group Leader | Cited by 3,244 | of Academisch Medisch Centrum Universiteit van Amsterdam, Amsterdam (AMC) | Read 49 publications | Contact Johan VAN NES
Activation of Toll-like receptor (TLR) signaling and related pathways by microbial products drives inflammatory responses, host defense pathways and adaptive immunity. The cost of excessive inflammation is cell and tissue damage, an…
He served as Associate Professor in Transdisciplinary Research at the Swedish Academy and as Associate Professor in Musicology at the University of Jyväskylä in Finland.
AMP-activated protein kinase (AMPK) is a phylogenetically conserved fuel-sensing enzyme that is present in all mammalian cells. During exercise, it is activated in skeletal muscle in humans, and at least in rodents, also in adipose tissue…
EWSR1 belongs to the FET family of RNA-binding proteins including also Fused in Sarcoma (FUS), and TATA-box binding protein Associated Factor 15 (TAF15). As consequence of the multifunctional role of EWSR1 leading to a high frequency of…
The heterotrimeric AMP-activated protein kinase (AMPK) plays a key role in regulating cellular energy metabolism; in response to a fall in intracellular ATP levels it activates energy producing pathways and inhibits energy consuming…
The 5′-AMP-activated protein kinase (AMPK) is a potent regulator of skeletal muscle metabolism and gene expression. AMPK is activated both in response to in vivo exercise and ex vivo contraction.