Rostoucí napětí a geopolitické výzvy vedou vlády k dlouhodobému zvyšování výdajů na obranu, což vytváří stabilní poptávku napříč celým dodavatelským řetězcem.
Human coronavirus OC43 [1 ] (HCoV-OC43) is a member of the species Betacoronavirus gravedinis, [2 ] which infects humans and cattle. [3 ] [4 ] The infecting coronavirus is an enveloped, positive-sense, single-stranded RNA virus that enters…
Coronavirus spike (S) glycoproteins mediate receptor binding, membrane fusion, and virus entry and determine host range. Murine betacoronavirus (β-CoV) in group A uses the N-terminal domain (NTD) of S protein to bind to its receptor…
The genome organization and expression strategy of the newly identified severe acute respiratory syndrome coronavirus (SARS-CoV) were predicted using recently published genome sequences.
Remdesivir (RDV), a broadly acting nucleoside analogue, is the only FDA approved small molecule antiviral for the treatment of Covid-19 patients. To date, there are no reports identifying SARS-CoV-2 RDV resistance in patients, animal models…
The S1 region of the spike glycoprotein is responsible for interacting with receptor molecules on the surface of the host cell in the first step of viral entry. [4 ] [7 ] S1 contains two domains, called the N-terminal domain (NTD) and C…
Central Nervous System (CNS) infections are one of the most critical problems in public health, as frequently patients exhibit neurologic sequelae. Usually, CNS pathologies are caused by known neurotropic viruses such as measles virus (MV…