Programmed death-ligand 1 (PD-L1) on cancer cells engages with programmed cell death-1 (PD-1) on immune cells, contributing to cancer immune escape. For multiple cancer types, the PD-1/PD-L1 axis is the major speed-limiting step of the anti…
The drug has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias. [7 ] It is still available in Australia, albeit with restrictions after an application by its manufacturer to review its…
Progressive cerebral deposition of the amyloid β-protein (Aβ) in brain regions serving memory and cognition is an invariant and defining feature of Alzheimer disease. A highly similar but less robust process accompanies brain aging in many…