GitHub - NAalytics/Assemblies-of-putative-SARS-CoV2-spike…
RNA vaccines have become a key tool in moving forward through the challenges raised both in the current pandemic and in numerous other public health and medical challenges. With the rollout of vaccines for Covid-19, these synthetic mRNAs…
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HIOC - Wikipedia
HIOC is a small-molecule agent which acts as a selective TrkB receptor agonist (active at at least 100 nM; prominent activation at 500 nM). [1 ] [2 ] [3 ] It was derived from N-acetylserotonin (NAS). [2 ] [3 ] [4 ] Relative to NAS, HIOC…
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Immunomodulatory effects of deacetylase inhibitors: therapeutic…
Classical zinc-dependent histone deacetylases (Hdacs) catalyse the removal of acetyl groups from histone tails and also from many non-histone proteins, including the transcription factor FOXP3, a key regulator of the development and…
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Plant derived substances with anti-cancer activity: from…
Plants have had an essential role in the folklore of ancient cultures. In addition to the use as food and spices, plants have also been utilized as medicines for over 5000 years. It is estimated that 70–95% of the population in developing…
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Cannabinoid Receptors and the Endocannabinoid System: Signaling…
The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled receptor family, cannabinoid receptors 1 (CB1R) and 2.
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Isoform-selective histone deacetylase inhibitors - PMC
Histone deacetylase (HDAC) proteins are transcription regulators linked to cancer. As a result, multiple small molecule HDAC inhibitors are in various phases of clinical trials as anti-cancer drugs.
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Nerve Growth Factor in Cancer Cell Death and Survival - PMC
One of the major challenges for cancer therapeutics is the resistance of many tumor cells to induction of cell death due to pro-survival signaling in the cancer cells. Here we review the growing literature which shows that neurotrophins…
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Doslovný záznam ze zasedání - Pondělí, 12. prosince 2005
Zpět na portál Europarl
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Estrogen receptor alpha in the brain mediates tamoxifen-induced…
Estrogen receptor alpha in the hypothalamus is required for the effects of chronic tamoxifen treament on gene expression, thermoregulation, bone, and movement in mice.
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