D) A549 cells treated with succinate showed increases in SNAI1, a transcription factor that promotes EMT. E) Metformin (which is an inhibitor of EMT [72 ]) abolished the migration responses of A549 cells to succinate.
Fillets from marine fish species contain n-3 polyunsaturated fatty acids (Pufas) in the form of phospholipids (PLs). To investigate the importance of PL-bound n-3 Pufas in mediating the anti-obesogenic effect of lean seafood, we compared…
Autism Spectrum Disorder (ASD) is a severe neurodevelopmental disorder. To enhance the understanding of the gut microbiota structure in ASD children at different ages as well as the relationship between gut microbiota and fecal metabolites…
Gut microbes supporting body growth are known but the mechanisms are less well documented. Using the microbial tryptophan metabolite indole, known to regulate prokaryotic cell division and metabolic stress conditions, we mono-colonized germ…
African American (AA) men with prostate cancer (PCa) have worse disease, with a higher incidence, younger age and more advanced disease at diagnosis, and a worse prognosis, compared to Caucasian (CA) men.