Nico Dantuma är professor i molekylär cellbiologi sedan 2011. Hans forskning handlar om betydelsen av ubikvitin-proteasomsystemet vid utvecklingen av neurodegenerativa sjukdomar och cancer, liksom behandlingspotentialen vid modifiering av…
An international, peer-reviewed, open access journal focusing on cancer research and the optimal use of preventative and integrated treatment interventions to achieve improved outcomes, enhanced survival and quality of life for the cancer…
MIV-711 is a highly potent and selective cathepsin K inhibitor. The current article summarizes the therapeutic effects of MIV-711 on joint pathology in rabbits subjected to anterior cruciate ligament transection (ACLT), and the prophylactic…
Monocyte chemoattractant protein-1 (MCP-1) is the first discovered and most extensively studied CC chemokine, and the amount of studies on its role in the etiologies of obesity- and diabetes-related diseases have increased exponentially…
Volker M. Lauschke (V.M.L.) is Professor in Translational Pharmacology at Karolinska Institutet (KI), Stockholm, Sweden and Director of the Biofabrication and Tissue Engineering Facility at KI.
Acetylcholinesterase is involved in the termination of impulse transmission by rapid hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the central and peripheral nervous systems.
For reasons that remain unclear, whether type 5 AC (AC5), one of two major AC isoforms in heart, is protective or deleterious in response to cardiac stress is controversial. To reconcile this controversy we examined the cardiomyopathy…
NMDA receptors (Nmdar) play an important role in neural plasticity including long-term potentiation and long-term depression, which are likely to explain their importance for learning and memory.