Critical Role of Acetylation in Tau-Mediated Neurodegeneration…
Tauopathies, including frontotemporal dementia (FTD) and Alzheimer’s disease (AD), are neurodegenerative diseases in which tau fibrils accumulate. Recent evidence supports soluble tau species as the major toxic species.
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White to brown fat phenotypic switch induced by genetic and…
Living in an enriched environment with complex physical and social stimulation leads to improved cognitive and metabolic health. In white fat, enrichment induced the upregulation of the brown fat cell fate determining gene Prdm16, brown fat…
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Dermatological adverse events with taxane chemotherapy - PMC
Taxanes (docetaxel and paclitaxel) are among the most commonly prescribed anticancer drugs approved for the treatment of metastatic or locally advanced breast, non-small cell lung, prostate, gastric, head and neck, and ovarian cancers, as…
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Dementia prevention, intervention, and care: 2020 report of the…
If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button.
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The TSC1–TSC2 complex: a molecular switchboard controlling cell…
TSC1 and TSC2 are the tumour-suppressor genes mutated in the tumour syndrome TSC (tuberous sclerosis complex). Their gene products form a complex that has become the focus of many signal transduction researchers.
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Mail On Sunday | Daily Mail Online
Daily Mail - news, sport, celebrity, science and health stories
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Activation of CDK4 triggers development of Non-Alcoholic Fatty…
The development of Non Alcoholic Fatty Liver Disease (Nafld) is a multiple step process. Here we show that activation of cdk4 triggers the development of Nafld. We found that cdk4 protein levels are elevated in mouse models of Nafld and in…
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Bengt Fadeel | Karolinska Institutet
Bengt Fadeel, MD, PhD, is a Professor of Medical Inflammation Research.He is also the Vice Chairman of the Institute of Environmental Medicine.Prof. Fadeel is a Fellow of the Academy of Toxicological Sciences (ATS) and Member of Academia…
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Third-party and independent candidates for the 2020 United…
Jorgensen was the only candidate to receive more than 2% of the vote in any one state.
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Henry Mancini – Wikipédia, a enciclopédia livre
Dono de um apuro estético muito sofisticado no arranjo de suas músicas e tendo sido um melodista excepcional, ele é melhor lembrado como sendo um dos mais conhecidos compositores de trilhas sonoras para a televisão e o cinema, ganhando um…
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