Tauopathies, including frontotemporal dementia (FTD) and Alzheimer’s disease (AD), are neurodegenerative diseases in which tau fibrils accumulate. Recent evidence supports soluble tau species as the major toxic species.
Living in an enriched environment with complex physical and social stimulation leads to improved cognitive and metabolic health. In white fat, enrichment induced the upregulation of the brown fat cell fate determining gene Prdm16, brown fat…
Taxanes (docetaxel and paclitaxel) are among the most commonly prescribed anticancer drugs approved for the treatment of metastatic or locally advanced breast, non-small cell lung, prostate, gastric, head and neck, and ovarian cancers, as…
TSC1 and TSC2 are the tumour-suppressor genes mutated in the tumour syndrome TSC (tuberous sclerosis complex). Their gene products form a complex that has become the focus of many signal transduction researchers.
Empathy theoretically serves an affiliative interpersonal function by satisfying motives for intimacy and union with others. Accordingly, empathy is expected to vary depending on the situation.
Bengt Fadeel, MD, PhD, is a Professor of Medical Inflammation Research.He is also the Vice Chairman of the Institute of Environmental Medicine.Prof. Fadeel is a Fellow of the Academy of Toxicological Sciences (ATS) and Member of Academia…
Por conta disso, a música folk, na cultura norte-americana, atingiu o auge de popularidade nas décadas de 1950 e 1960 e Bob Dylan incorporou as tensões dessa época da melhor forma, com foco nos detalhes e humor. [4 ]
Dono de um apuro estético muito sofisticado no arranjo de suas músicas e tendo sido um melodista excepcional, ele é melhor lembrado como sendo um dos mais conhecidos compositores de trilhas sonoras para a televisão e o cinema, ganhando um…