Therapeutic antibodies that block the programmed death-ligand 1 (PD-L1)/programmed death-1 (PD-1) pathway can induce robust and durable responses in patients with various cancers, including metastatic urothelial cancer (mUC)1–5.
Over 50 years of research have established that cognitive processes influence pupil size. This has led to the widespread use of pupil size as a peripheral measure of cortical processing in psychology and neuroscience.
Hereditary cancer syndromes (HCSs) are arguably the most frequent category of Mendelian genetic diseases, as at least 2% of presumably healthy subjects carry highly-penetrant tumor-predisposing pathogenic variants (PVs).
Soluble amyloid-β (Aβ) aggregates of various sizes, ranging from dimers to large protofibrils, have been associated with neurotoxicity and synaptic dysfunction in Alzheimer's Disease (AD).
Roles of all-trans-retinoic acid (tRA), a metabolite of vitamin A (VA), in both tolerogenic and immunogenic responses are documented. However, how tRA affects the development of systemic autoimmunity is poorly understood.
Blank picture, 3 x 2 pixels; good for a placeholder when you need it to assume a 3:2 aspect ratio. See Image:Blank300.png for a placeholder which won't take up any visible vertical space, and Image:Blank300vert.png for a horizontal one.
In addition, distinct mutational signatures, for example, SBS6, and overall mutational load, somatic mutations in Pabpc1, Pabpc3, and TFAM co-segregated with the resistance status, high-grade serous carcinoma subtype, or overall survival of…
Aprswxnet Membership Report prepared (MST):07/08/2025 03:56 Nwsid Call/CW Location Name AP004 KF4HJW Tide, VA, US Darrel Sutton AP009 N5JXS Colorado Springs, CO, US Gerry Creager AP014 WA2GUG Cairo, NY, US Charlie Calfano AP016 KB4JHU-15…