The diversity of polyubiquitin-C means that ubiquitylation contributes to the regulation of many cellular events. Polyubiquitin-C doesn’t activate the heat-shock response, but it plays a key role in sustaining the response.
Following the hypothesis that the public databases contain cloned mRNAs that would be degraded in vivo by the nonsense-mediated mRNA decay mechanism, 144 isoform sequences deposited in Swiss-PROT have been identified that derive from mRNAs…
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Many RNA regulatory proteins controlling pre-mRNA splicing contain serine:arginine (SR) repeats. Here we found that these SR domains bound hydrogel droplets composed of fibrous polymers of the low-complexity domain of heterogeneous…
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