PGC-1α and exercise intensity dependent adaptations in mouse…
The aim of the present study was to examine the role of PGC-1α in intensity dependent exercise and exercise training-induced metabolic adaptations in mouse skeletal muscle. Whole body PGC-1α knockout (KO) and littermate wildtype (WT) mice…
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Guidance Molecules in Vascular Smooth Muscle - PMC
Several highly conserved families of guidance molecules, including ephrins, Semaphorins, Netrins, and Slits, play conserved and distinct roles in tissue remodeling during tissue patterning and disease pathogenesis.
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Impact of Diabetes on Cardiovascular Disease: An Update - PMC
Cardiovascular diseases are the most prevalent cause of morbidity and mortality among patients with type 1 or type 2 diabetes. The proposed mechanisms that can link accelerated atherosclerosis and increased cardiovascular risk in this…
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Exercise-Stimulated ROS Sensitive Signaling Pathways in…
Physical exercise represents a major challenge to whole-body homeostasis, provoking acute and adaptative responses at the cellular and systemic levels. Different sources of reactive oxygen species (ROS) have been described in skeletal…
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Caloric restriction preserves memory and reduces anxiety of…
Neurovascular integrity plays an important role in protecting cognitive and mental health in aging. Lifestyle interventions that sustain neurovascular integrity may thus be critical on preserving brain functions in aging and reducing the…
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Rodger’s Solitude Patern
MIME-Version: 1.0 Content-Type: multipart/related; boundary="-_NextPart_01C8F288.9A2B6B70" This document is a Single File Web Page, also known as a Web Archive file.
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Mitochondrial dysfunction and oxidative stress activate…
Oxidative stress and low-grade inflammation are the hallmarks of the aging process and are even more enhanced in many age-related degenerative diseases. Mitochondrial dysfunction and oxidative stress can provoke and potentiate inflammatory…
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