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Lipidomics is systems-level analysis and characterization of lipids and their interacting moieties. The amount of information in the genomic and proteomic fields is greater than that in the lipidomics field, because of the complex nature of…
Changes in the mesolimbic dopamine (DA) system are implicated in a range of neuropsychiatric conditions including addiction, depression and schizophrenia. Dysfunction of the neuroimmune system is often comorbid with such conditions and…
Respiratory cilia are the driving force of the mucociliary escalator, working in conjunction with secreted airway mucus to clear inhaled debris and pathogens from the conducting airways.
Brain phosphatidylcholine (PC) levels are regulated by a balance between synthesis and hydrolysis. Pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1α/β) activate phospholipase A2 (PLA2) and PC…
Director of Software Solutions | AI & SaaS Innovator | 13+ Years Product Development experience in Software, Manufacturing, IoT, and Industrial Automation | 4X Patent Holder | EB1-A (Einstein Visa Recipient) · Driven by curiosity and a…
Mutations in the metabolic enzymes isocitrate dehydrogenase 1 (IDH1) and IDH2 in cancer implicate altered metabolism in tumorigenesis. These mutations alter the enzymes such that they reduce the TCA cycle intermediate 2OG to the…