Transgenerational epigenetic inheritance is the proposed transmission of epigenetic markers and modifications from one generation to multiple subsequent generations without altering the primary structure of DNA. [1 ] Thus, the regulation of…
Over the past century, socio-environmental evolution (e.g., reduced pathogenic load, decreased physical activity [PA], improved nutrition) led to cumulative increments in maternal energy resources (i.e., body mass, adiposity) and decrements…
Lamarckism, also known as Lamarckian inheritance or neo-Lamarckism, [2 ] is the notion that an organism can pass on to its offspring physical characteristics that the parent organism acquired through use or disuse during its lifetime.
Macronutrients and trace elements are important components of living tissues that have different metabolic properties and functions. Trace elements participate in the regulation of immunity through humoral and cellular mechanisms, nerve…
Andromeda has a D25 isophotal diameter of about 46.56 kiloparsecs (152,000 light-years) [8 ] and is approximately 765 kpc (2.5 million light-years) from Earth.
Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and function and constitute risk factors for cognitive impairment. Alterations to taurine homeostasis can impact a number of biological processes, such as…
Controlled oxidation, such as disulfide bond formation in sperm nuclei and during ovulation, plays a fundamental role in mammalian reproduction. Excess oxidation, however, causes oxidative stress, resulting in the dysfunction of the…
Interest in transgenerational epigenetic inheritance has intensified with the boosting of knowledge on epigenetic mechanisms regulating gene expression during development and in response to internal and external signals such as biotic and…
This paper proposes association as a foundational explanatory principle that bridges the longstanding divide between upward and downward causation in biological systems. Moving beyond the limitations of reductive physicalism and dualist…