Since the 1990s, pRb was known to be inactivated via phosphorylation. Until, the prevailing model was that Cyclin D- Cdk 4/6 progressively phosphorylated it from its unphosphorylated to its hyperphosphorylated state (14+ phosphorylations).
JCI South Bohemia, z.s. | 54 sledujících uživatelů na LinkedIn. Developing Leaders For a Changing World | Jsme nezisková mezinárodní organizace pro mladé aktivní lidi, kteří nejsou lhostejní ke svému okolí a sami se chtějí aktivně rozvíjet…
BCAR1 is a ubiquitously expressed adaptor molecule originally identified as the major substrate of v-Src and v-Crk . p130Cas/BCAR1 belongs to the Cas family of adaptor proteins and can act as a docking protein for several signalling…
Curcumin, a phytochemical isolated from curcuma plants which are used as coloring ingredient for the preparation of curry powder, has several activities which suggest that it might be an interesting drug for the treatment or prevention of…