With the rapid expansion of aging biology research, the identification and evaluation of longevity interventions in humans have become key goals of this field. Biomarkers of aging are critically important tools in achieving these objectives…
Cardiovascular disease (CVD) and cancer are the two leading causes of death worldwide. Although commonly thought of as two separate disease entities, CVD and cancer possess various similarities and possible interactions, including a number…
Adrenaline, also known as epinephrine and alternatively spelled adrenalin, is a hormone and medication [10 ] [11 ] which is involved in regulating visceral functions (e.g., respiration). [10 ] [12 ] It appears as a white microcrystalline…
Hypertension has been linked with peripheral and central reductions in vascular density, and with devastating effects on brain function. However, the underlying mechanisms in the relationship between blood pressure and cognitive impairment…
Focalization, concentration, of consciousness are of its essence." [2 ] Attention has also been described as the allocation of limited cognitive processing resources. [3 ] Attention is manifested by an attentional bottleneck, in terms of…
Bone is a crucial element of the skeletal-locomotor system, but also functions as an immunological organ that harbors hematopoietic stem cells (HSCs) and immune progenitor cells. Additionally, the skeletal and immune systems share a number…
Alpha-synuclein is a protein implicated in Parkinson’s disease and thought to be one of the main pathological drivers in the disease, although it remains unclear how this protein elicits its neurotoxic effects.
This series highlights 60 + 1 historical discoveries of significant impact to the nephrology community. So that the selection of discoveries was globally representative, the leadership of the ten ISN Regional Boards were asked to provide…