Alzheimer's Disease (AD) is characterized by cerebral accumulation of β-amyloid peptides (Aβ), which are proteolytically derived from β-amyloid precursor protein (βAPP). βAPP metabolism is highly regulated via various signal transduction…
Mark Twain, pseudonimo di Samuel Langhorne Clemens (Florida, 30 novembre 1835 – Redding, 21 aprile 1910), è stato uno scrittore, umorista, aforista e docente statunitense autore di capolavori riconosciuti della letteratura statunitense del…
Disrupted circadian or 24-h rhythms are among the most common early findings in a wide range of neurodegenerative disorders. Once thought to be a mere consequence of the disease process, increasing evidence points toward a causal or…