Darell Bigner | Duke University Medical Center, Durham | DUMC…

Darell Bigner | Cited by 86,326 | of Duke University Medical Center, Durham (DUMC) | Read 1018 publications | Contact Darell Bigner
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Barcelona - Wikipedia

Barcelona (/ ˌ b ɑːr s ə ˈ l oʊ n ə/ BAR-sə- LOH-nə; Catalan: [bəɾsəˈlonə] ; Spanish: [baɾθeˈlona] ) is a city on the northeastern coast of Spain.
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LiG Metrology, Correlated Error, and the Integrity of the…

The published 95% uncertainty of the global surface air-temperature anomaly (Gsata) record through 1980 is impossibly less than the 2σ = ±0.25 °C lower limit of laboratory resolution of 1 °C/division liquid-in-glass (LiG) thermometers.
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(PDF) Plant mutation breeding in agriculture

A mutation is a sudden heritable change in the DNA in a living cell, not caused by genetic segregation or genetic recombination. Mutation breeding is the purposeful application of mutations in plant breeding.
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Anti-inflammatory activity of curcumin-loaded tetrahedral…

Gouty arthritis is a very familiar inflammatory arthritis. Controlling inflammation is the key to preventing gouty arthritis. However, colchicine, the most highly represented drug used in clinical practice, has strict contraindications…
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Synapses with inhibitory neurons differentiate anterior…

The primate dorsolateral prefrontal cortex (Dlpfc) and anterior cingulate cortex (ACC) focus attention on relevant signals and suppress noise in cognitive tasks. However, their synaptic interactions and unique roles in cognitive control are…
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CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T…

Immune checkpoint blockade, exemplified by antibodies targeting the programmed death-1 (PD-1) receptor, can induce durable tumor regressions in some patients. To enhance the efficacy of existing immunotherapies, we screened for small…
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Induction of Proinflammatory Responses in Macrophages by the…

The proinflammatory cytokines produced by the innate immune system in response to pathogenic infection protect the host by controlling microbial growth. However, excessive proinflammatory responses could disrupt the host’s vital…
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The Seasonal Reading Challenge - Spring Challenge 2012: FIRE…

49 discussion posts. Sandy said: If you'd like a place to plan what you'll be reading for the Spring 2012 Challenge, you may post a list in this thread. ...
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Poorly Neutralizing Cross-Reactive Antibodies against the…

The human antibody response to flavivirus infection is dominantly directed against a cross-reactive epitope on the fusion loop of domain II (DII-FL) of the envelope (E) protein. Although antibodies against this epitope fail to recognize…
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