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Alzheimer's disease (AD) and age-related cognitive decline represent a growing health burden and involve the hippocampus, a vulnerable brain region implicated in learning and memory.
At a molecular and cellular level, several pathways and biomarkers are associated with ageing; Lopez-Otin et al. described and categorized the hallmarks that reflect the mammalian ageing process [2]; the brain ageing hallmarks [6] mostly…
Compared to other imaging modalities, SERS imaging does not have these limitations, and can in theory provide high degrees of multiplexed detection, on par with specialized ex vivo imaging methods like multiplexed histology,[146-148] or…