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BRCA
Námi iniciovaná reportáž, tentokrát na televizi Seznam o rakovině vaječníků a genetické mutaci BRCA s prof. Davidem Cibulou, RNDr. Janou Soukupovou a pacientkou Caroline.
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BRCA :: Biolife
Mutace BRCA se podílejí na vzniku rakoviny prsu a vaječníků. BRCA1 a BRCA2 jsou tumor supresorové geny, které jsou inaktivovány během nádorového vývoje karcinomu prsu.Zárodečné mutace těchto dvou genů se přenášejí autozomálně dominantním…
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BRCA1 - Wikipedia
BRCA1 je dio kompleksa koji popravlja dvostruke niti u DNK. Lanci dvostruke zavojnice DNK neprekidno se lome jer se oštećuju.
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Role of natural compounds in preventing and treating breast…
Breast cancer (BrCa) is the most commonly diagnosed cancer and the second leading cause of cancer-related death in women. Alarming increases in the cases quests for more effective treatment of BrCa.
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Mechanisms of inherited cancer susceptibility - PMC
A small proportion of many cancers are due to inherited mutations in genes, which result in a high risk to the individual of developing specific cancers. There are several classes of genes that may be involved: tumour suppressor genes…
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Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the…
The BRCA-1 protein is a tumor suppressor involved in repair of DNA damage. Epigenetic mechanisms contribute to its reduced expression in sporadic breast tumors. Through diet, humans are exposed to a complex mixture of xenobiotics and…
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Biomarkers Predicting Progression and Prognosis of Ductal…
However, several transcriptomic changes in the luminal epithelium may play a role in cancer hallmarks. These include genes involved in cell cycle control [MKI67 (Ki-67), CDNK2A (p16), Aurka (Aurora kinase A), BCL9 (B-cell CLL/lymphoma 9…
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Carcinogenesis - Wikipedia
Only certain mutations lead to cancer whereas the majority of mutations do not.[ citation needed]
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Bipolar I Disorder and Schizophrenia: A 440–Single-Nucleotide…
Bipolar, schizophrenia, and schizoaffective disorders are common, highly heritable psychiatric disorders, for which familial coaggregation, as well as epidemiological and genetic evidence, suggests overlapping etiologies.
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