Apoptotic cells promote their own clearance and immune…

Effective clearance of apoptotic cells by macrophages is essential for immune homeostasis. The transcriptional pathways that allow macrophages to sense and respond to apoptotic cells are poorly defined.
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Neutrophil swarms require LTB4 and integrins at sites of cell…

Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2.
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MicroRNAs Reprogram Normal Fibroblasts into Cancer Associated…

Cancer associated fibroblasts (CAFs) are a major constituent of the tumor stroma, but little is known about how cancer cells transform normal fibroblasts into CAFs. miRNAs are small noncoding RNA molecules that negatively regulate gene…
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Lymphocyte Circadian Clocks Control Lymph Node Trafficking and…

Lymphocytes circulate through lymph nodes (LN) in search for antigen in what is believed to be a continuous process. Here, we show that lymphocyte migration through lymph nodes and lymph occurred in a non-continuous, circadian manner.
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Neutrophil Recruitment to Lymph Nodes Limits Local…

Published in the journal: . PLoS Pathog 11(4): e32767. doi:10.1371/journal.ppat.1004827 Category: Research Article doi: https://doi.org/10.1371/journal.ppat.1004827
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Fibroblastic Reticular Cells Guide T Lymphocyte Entry Into and…

Although a great deal is known about T cell entry into lymph nodes (LNs)3, much less is understood about how T lymphocytes access the splenic white pulp (WP). We show here that, as recently described for LNs, fibroblastic reticular cells…
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Cannabidiol and Cannabigerol Exert Antimicrobial Activity…

Cannabidiol (CBD) and cannabigerol (CBG) are two pharmacologically active phytocannabinoids of Cannabis sativa L. Their antimicrobial activity needs further elucidation, particularly for CBG, as reports on this cannabinoid are scarce.
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Adventitial fibroblasts direct smooth muscle cell-state…

Transition from healthy to diseased state is a cell-type-specific process, influenced by neighboring cells and resulting in functionally meaningful differences between pulmonary artery adventitial fibroblasts and smooth muscle cells.
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Haofei WANG | PhD candidate | Bachelor of Engineering | The…

Haofei WANG, PhD candidate | Cited by 794 | of The University of Queensland, Brisbane (UQ) | Read 15 publications | Contact Haofei WANG
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