Apoptotic cells promote their own clearance and immune…

Effective clearance of apoptotic cells by macrophages is essential for immune homeostasis. The transcriptional pathways that allow macrophages to sense and respond to apoptotic cells are poorly defined.
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Cannabidiol and Cannabigerol Exert Antimicrobial Activity…

Cannabidiol (CBD) and cannabigerol (CBG) are two pharmacologically active phytocannabinoids of Cannabis sativa L. Their antimicrobial activity needs further elucidation, particularly for CBG, as reports on this cannabinoid are scarce.
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Neutrophil Recruitment to Lymph Nodes Limits Local…

Published in the journal: . PLoS Pathog 11(4): e32767. doi:10.1371/journal.ppat.1004827 Category: Research Article doi: https://doi.org/10.1371/journal.ppat.1004827
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BRD4 connects enhancer remodeling to senescence immune…

Oncogene-induced senescence is a potent barrier to tumorigenesis that limits cellular expansion following certain oncogenic events. Senescent cells display a repressive chromatin configuration thought to stably silence proliferation…
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MicroRNAs Reprogram Normal Fibroblasts into Cancer Associated…

Cancer associated fibroblasts (CAFs) are a major constituent of the tumor stroma, but little is known about how cancer cells transform normal fibroblasts into CAFs. miRNAs are small noncoding RNA molecules that negatively regulate gene…
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In Vitro and In Vivo Antifungal Profile of a Novel and Long…

The profile of PC945, a novel triazole antifungal designed for administration via inhalation, was assessed in a range of in vitro and in vivo studies. PC945 was characterized as a potent, tightly binding inhibitor of Aspergillus fumigatus…
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Haofei WANG | PhD candidate | Bachelor of Engineering | The…

Haofei WANG, PhD candidate | Cited by 794 | of The University of Queensland, Brisbane (UQ) | Read 15 publications | Contact Haofei WANG
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Platelets release mitochondria serving as substrate for…

When activated and in platelet storage bags, platelets release respiratory-competent mitochondria, a recognized damage-associated molecular pattern. Mitochondria, descendant of Rickettsia prowazekii, serve as substrate for bactericidal sPLA…
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Adventitial fibroblasts direct smooth muscle cell-state…

Transition from healthy to diseased state is a cell-type-specific process, influenced by neighboring cells and resulting in functionally meaningful differences between pulmonary artery adventitial fibroblasts and smooth muscle cells.
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170 questions with answers in RAW 264.7 | Science topic

Review and cite RAW 264.7 protocol, troubleshooting and other methodology information | Contact experts in RAW 264.7 to get answers
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