Steve Widdicombe, Head of Department | Cited by 13,650 | of Plymouth Marine Laboratory, Plymouth (PML) | Read 241 publications | Contact Steve Widdicombe
The Tead family transcription factors are the major intracellular mediators of the Hippo-Yap pathway. Despite the importance of Hippo signaling in tumorigenesis, Tead-dependent downstream oncogenic programs and target genes in cancer cells…
The microbiome of Crohn’s disease (CD) patients is composed of a microbial community that is considered dysbiotic and proinflammatory in nature. The overrepresentation of Enterobacteriaceae species is a common feature of the CD microbiome…
While most cigarette smokers endorse a desire to quit smoking, only about 14% to 49% will achieve abstinence after 6 months or more of treatment. A greater understanding of the effects of smoking on brain function may (in conjunction with…
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It was formed on December 2, 1925 from a merger of six chemical companies: Agfa, BASF, Bayer, Griesheim-Elektron, Hoechst, and Weiler-ter-Meer. [2 ] It was seized by the Allies after World War II and split into its constituent companies…
Ann Nordgren is Professor and Senior Physician of Clinical Genetics. She received her medical degree in 1991, licence to practice medicine 1993 and PhD degree 2001 at Karolinska Institute, Sweden, and became board certified specialist in…