p53-repressed miRNAs are involved with E2F in a feed-forward…
Normal cell growth is governed by a complicated biological system, featuring multiple levels of control, often deregulated in cancers. The role of microRNAs (miRNAs) in the control of gene expression is now increasingly appreciated, yet…
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The cell cycle: a review of regulation, deregulation and…
Abstract. The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This review will focus on these mechanisms, i.e. regulation of cyclin‐dependent kinases (CDK) by cyclins, CDK inhibitors and phosphorylating…
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Human Papillomavirus 16 E7 Stabilizes Apobec3A Protein by…
Apobec3 (A3) mutation signatures have been observed in a variety of human cancer genomes, including those of cervical and head and neck cancers caused by human papillomavirus (HPV) infection.
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Protective Role of Polyphenols against Vascular Inflammation…
Aging is a major risk factor in the development of chronic diseases affecting various tissues including the cardiovascular system, muscle and bones. Age-related diseases are a consequence of the accumulation of cellular damage and reduced…
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The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor…
P53 is a transcription factor highly inducible by many stress signals such as DNA damage, oncogene activation, and nutrient deprivation. Cell-cycle arrest and apoptosis are the most prominent outcomes of p53 activation.
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Hwanggeumchal sorghum Induces Cell Cycle Arrest, and Suppresses…
Cancer is one of the highly virulent diseases known to humankind with a high mortality rate. Breast cancer is the most common cancer in women worldwide. Sorghum is a principal cereal food in many parts of the world, and is critical in folk…
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EZH2 is downstream of the pRB-E2F pathway, essential for…
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
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2016 in American music - Wikipedia
The following is a list of events and releases that happened in 2016 in music in the United States.
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p53 - Wikipedia
This image shows different patterns of p53 expression in endometrial cancers on chromogenic immunohistochemistry, whereof all except wild-type are variably termed abnormal/aberrant/mutation-type and are strongly predictive of an underlying…
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Translation Stress Regulates Ribosome Synthesis and Cell…
Ribosome and protein synthesis are major metabolic events that control cellular growth and proliferation. Impairment in ribosome biogenesis pathways and mRNA translation is associated with pathologies such as cancer and developmental…
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